Drug metabolism and disposition: the biological fate of chemicals

In vitro and in vivo correlation of hepatic transporter effects on erythromycin metabolism: characterizing the importance of transporter-enzyme interplay.

Lam JL, Okochi H, Huang Y, Benet LZ

In vitro and in vivo correlation of hepatic transporter effects on erythromycin metabolism: characterizing the importance of transporter-enzyme interplay.

Drug metabolism and disposition: the biological fate of chemicals

Lam JL, Okochi H, Huang Y, Benet LZ

Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.

Drug metabolism and disposition: the biological fate of chemicals

Lau YY, Okochi H, Huang Y, Benet LZ

Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.

Drug metabolism and disposition: the biological fate of chemicals

Lau YY, Okochi H, Huang Y, Benet LZ

Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein.

Drug metabolism and disposition: the biological fate of chemicals

Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET

Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein.

Drug metabolism and disposition: the biological fate of chemicals

Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET

Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes.

Drug metabolism and disposition: the biological fate of chemicals

Lam JL, Benet LZ

Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes.

Drug metabolism and disposition: the biological fate of chemicals

Lam JL, Benet LZ

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin.

Drug metabolism and disposition: the biological fate of chemicals

Sun H, Huang Y, Frassetto L, Benet LZ

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin.

Drug metabolism and disposition: the biological fate of chemicals

Sun H, Huang Y, Frassetto L, Benet LZ

Hair Analytical Lab

Drug metabolism and disposition: the biological fate of chemicals

In vitro and in vivo correlation of hepatic transporter effects on erythromycin metabolism: characterizing the importance of transporter-enzyme interplay.

In vitro and in vivo correlation of hepatic transporter effects on erythromycin metabolism: characterizing the importance of transporter-enzyme interplay.

Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.

Pharmacokinetics of atorvastatin and its hydroxy metabolites in rats and the effects of concomitant rifampicin single doses: relevance of first-pass effect from hepatic uptake transporters, and intestinal and hepatic metabolism.

Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein.

Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein.

Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes.

Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes.

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin.

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin.

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Drug metabolism and disposition: the biological fate of chemicals

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